TIAFT - The International Association of Forensic Toxicologists
Back from Brisbane

President's message

Back from Brisbane...

The Brisbane meeting proved to be one of our best with 510 participants including 35 students from 46 countries. I would like to take this opportunity to thank the chair of the meeting, Olaf Drummer and his wonderful team for their hard work, dedication, and selfless service to make the 54th meeting successful.

Antalya 2016

2nd Regional TIAFT Meeting

Antalya - TURKEY

October 30th - November 2nd, 2016

TIAFT 2016 - Costa Rica

XII TIAFT Latin-American Regional Meeting


November 9th 12th, 2016

Latest News

The TIAFT List of Therapeutic and Toxic Values of Drugs has been permanently removed from the TIAFT website.
Please read the full note

TIAFT List of Therapeutic and Toxic Values of Drugs

The TIAFT List of Therapeutic and Toxic Values of Drugs has been permanently removed from the TIAFT website. While databases of concentrations can be useful in assisting interpretations of toxicology results there are many factors that must be specifically considered when interpreting postmortem drug concentrations. These may include, but are not limited to:

  • route of administration and bioavailability,
  • single versus multiple doses (acute vs chronic administration),
  • tolerance and sensitization,
  • drug synergism and antagonism,
  • pharmacogenetics,
  • site dependence and condition/quality of specimen,
  • postmortem redistribution and interval,
  • specimen containers and drug stability.

With so many variables, postmortem interpretation of drug concentrations should be made in context, with a careful review of case history and giving consideration to analytical and pre-analytical variables.

For this reason the TIAFT Board has decided a more holistic review of laboratory data is not only essential but critical, and therefore TIAFT is no longer providing this data which, for practical reasons, cannot account for all the possible variables. There are published sources available which review the data in the literature available for the pharmacology and toxicology of various drugs. These are good starting points to begin the interpretive process.

Two of the more widely relied upon include:

  • Disposition of Toxic Drugs and Chemicals in Man, Tenth Edition, Randall C. Baselt, editor. Biomedical Publications, Seal Beach, CA, USA 2014.
  • Clarke’s Analysis of Drugs and Poisons, Fourth Edition, Anthony C. Moffat, M. David Osselton, Brian Widdop and Jo Watts, editors. Pharmaceutical Press, London & Chicago, 2011.

Additionally, there are numerous articles and reviews available in the scientific literature, many of which are open access.

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