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TIAFT - The International Association of Forensic Toxicologists
58th TIAFT Meeting 2020 - Cape Town, South Africa

The 58th TIAFT Annual Meeting

Cape Town - South Africa

October 31th - November 5th, 2020

The CTICC

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President's message

President's message

WARNING: There is Fake News in this Message

Is it just me, or does it seem like 2019 has passed us by at a record pace? The holiday season is already upon us, and the year’s end is clearly in sight...

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The TIAFT List of Therapeutic and Toxic Values of Drugs has been permanently removed from the TIAFT website.
Please read the full note

TIAFT List of Therapeutic and Toxic Values of Drugs

The TIAFT List of Therapeutic and Toxic Values of Drugs has been permanently removed from the TIAFT website. While databases of concentrations can be useful in assisting interpretations of toxicology results there are many factors that must be specifically considered when interpreting postmortem drug concentrations. These may include, but are not limited to:

  • route of administration and bioavailability,
  • single versus multiple doses (acute vs chronic administration),
  • tolerance and sensitization,
  • drug synergism and antagonism,
  • pharmacogenetics,
  • site dependence and condition/quality of specimen,
  • postmortem redistribution and interval,
  • specimen containers and drug stability.

With so many variables, postmortem interpretation of drug concentrations should be made in context, with a careful review of case history and giving consideration to analytical and pre-analytical variables.

For this reason the TIAFT Board has decided a more holistic review of laboratory data is not only essential but critical, and therefore TIAFT is no longer providing this data which, for practical reasons, cannot account for all the possible variables. There are published sources available which review the data in the literature available for the pharmacology and toxicology of various drugs. These are good starting points to begin the interpretive process.

Two of the more widely relied upon include:

  • Disposition of Toxic Drugs and Chemicals in Man, Tenth Edition, Randall C. Baselt, editor. Biomedical Publications, Seal Beach, CA, USA 2014.
  • Clarke’s Analysis of Drugs and Poisons, Fourth Edition, Anthony C. Moffat, M. David Osselton, Brian Widdop and Jo Watts, editors. Pharmaceutical Press, London & Chicago, 2011.

Additionally, there are numerous articles and reviews available in the scientific literature, many of which are open access.

The Journal of Analytical Toxicology

The Journal of Analytical Toxicology (JAT) is an international toxicology journal devoted to the timely dissemination of scientific communications concerning potentially toxic substances and drug identification, isolation, and quantitation.

Since its inception in 1977, the The Journal of Analytical Toxicology has striven to present state-of-the-art techniques used in toxicology labs. The peer-review process provided by the distinguished members of the Editorial Advisory Board ensures the high-quality and integrity of articles published in the Journal of Analytical Toxicology. Timely presentation of the latest toxicology developments is ensured through Technical Notes, Case Reports, and Letters to the Editor.

The articles published in the The Journal of Analytical Toxicology describe the chemical analysis of prescription drugs, drugs of abuse, pharmaceuticals, pesticides, industrial chemicals, and environmental toxins. JAT also contains information about known and recently identified poisons.

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Forensic Toxicology