SOFT - TIAFT 1998 October 5-9, 1998 Albuquerque, New Mexico, USA

Scientific Session 1 Moderators: Edward Cone, Ph.D., Anya Pierce, Ph.D. (click names for picture) Safety of Buprenorphine: Ceiling for Cardio-Respiratory and Subjective Effects at High IV Doses M. Huestis Disposition of Heroin and Metabolites in Multiple Biological Matrices after Low Dose Oral Heroin Administration in Humans A. Jenkins The Role of Ethanol in the Etiology of Heroin-Related Deaths A. Polettini Heroin Metabolites in the Blood of Car Drivers M. Bogusz Methadone Poisoning in Children J. Eastwood Acetylcodeine, an Impurity of Illicit Heroin: Pharmacological Evaluation and Interaction with Diacetylmorphine C. O'Neal 6-Acetylcodeine as a Urine Marker to Differentiate the Use of Street Heroin and Pharmaceutical Heroin R. Brenneisen A Prospective Analysis of Urine Specimens Taken from Suspected Hospital Overdose Admission Patients J. Lewis Scientific Session 2 Moderators: Maciej Bogusz, M.D., Ph.D., Marilyn Huestis, Ph.D. (click names for picture) Detection Times of Morphine and 6-Acetylmorphine in Urine after Intravenous Heroin E. Cone Detection Times of 6-Acetylmorphine, Free-morphine and Total-morphine in Urine after Smoking Heroin M. Smith Concordance of 6-Acetylmorphine with Free and Total Morphine in Urine After Intravenous, Intramuscular and Intranasal Heroin Administration W. Darwin Identification and Measurement of Hydrocodone in Urine Following Codeine Administration J. Oyler A Practical Approach for Identifying Opiate Users in Workplace Drug Testing Programs with Simultaneous Detection of Codeine, Morphine and 6-Acetylmorphine in Urine B. Paul Urine Adulteration: Why is this Urine "Klear"? How Much Klear is Required to Produce a Failed GC/MS Analysis for 9-Carboxy-THC and Opiates? M. Robertson Lack of Correlation Between Performance Impairment and Pharmacokinetic Measures During the Distribution Phase Following Marijuana Smoking S. Heishman Quantitation of D9-THC in Commercially Available Hemp Seed Oil Products K. Cole Poster Session 1 Moderator: Betty Buchan, Ph.D. Buprenorphine, Norbuprenorphine and Melanin in Human Hair D.Wilkins 3H-Cocaine/benzoylecgonine Uptake by Keratinocytes and Melanocytes in Culture G. Skopp Segmental and Total Hair Analysis to Monitor Substance Abuse During Pregnancy K. Hold Quantitation of Cocaine, Benzoylecgonine, Cocaethylene, Methylecgonine and Norcocaine in Human Hair by PICI GC/MS/MS J. Bourland Determination of Dextromethorphan in Drug Abuser's Hair by GC/MS H. Chung Analytical Results Prior to and after Hair Treatment by Ultra Clean G. Skopp Effect of Various Stripping Treatments on Analytical Results T. Donahue Cannabinoids Detection in Human Hair Washed with Cannabio Shampoo V. Cirimele Detection of Cocaine and Its Metabolites in Saliva and Urine by GC/MS during Clinical Drug Withdrawal I. Speckl Saliva and Plasma Testing for Drugs of Abuse I: Comparison of the Disposition and Pharmacological Effects of Cocaine E. Moolchan Saliva and Plasma Testing for Drugs of Abuse II: A Comparison of Pharmacological Effects and Disposition of Codeine J. Oyler Recruitment of Participants for Human Research Studies on Drugs of Abuse B. King Evaluation of an On-Site Method for Detection of Drugs of Abuse in Saliva C. Malcolm Comparison of the STC Methamphetamine Micro-Plate EIA for Urine and Oral Fluid J. Simer Sweat Testing for Drugs of Abuse II: Comparison of Codeine Disposition in Sweat Collected with a Heated Sweat patch Device and the PharmChek Sweat Patch R. Joseph Relationship of Pharmacological Effects to Codeine Concentrations in Plasma D. Lafko Partitioning of Morphine and its Glucuronides in Subcompartments of Blood G. Skopp Postmortem Findings of Foetal Drug Exposure in a Drug Abusing Mother G. Skopp Endogenous Morphine-A Protagonist in Pain Mechanism? C Neri Mortality Associated with Methadone Programs O. Drummer Urinary Excretion of 11-nor-9-carboxy-D9-THC and Cannabinoids in Drug Users A. Smith-Kieland Simultaneous Determination of D9-THC and 11-nor-9-carboxy-D9-THC in Human Plasma by SPE and GC-NICI-MS W. Huang Effect of the Detoxifying Carbohydrate Drink The Ultimate Blend on Urine Screening for Cannabinoids G. Skopp The Effect of Consumption of Hempenale on Urine Cannabinoid Screens G. Kunsman Cannabinoid Urine Positives After Ingestion of Hemp Seed Oil J. Vasiliades Poster Session 2 Moderator: Donna Bush, Ph.D. Comparison of Immunochromatographic Rapid Tests for Screening of Benzodiazepines, Amphetamine and Its Derivatives (Ecstasy) in Urine L. von Meyer Amphetamines Detection in Urine with Laboratory and On-Site Immunoassays: Effect of Antibody Specificity S. Bogema Evaluation of Three Immunochromatographic Rapid Tests for Screening of Amphetamine, Benzodiazepines and Cocaine in Urine M. Kraft Methadone Conversion to Methadone Metabolite during GC/MS Analysis of Urine Samples R. Galloway Performance of the CEDIA EDDP (Methadone Metabolite) Assay (a) P. Orsulak Clinical Application of the CEDIA EDDP (Methadone Metabolite) Assay (b) P. Orsulak Use of the Immulite Chemiluminescence Immunoassay System for Screening of Postmortem and DUID Blood Specimens J. Saady Urine Concentrations of Benzodiazepines, Including Flunitrazepam After a Single Oral Dose, Using Cassett COBAS INTEGRA Serum Benzodiazepines Assay K. Schwenzer Application of the Cassett COBAS INTEGRA Serum Barbiturates Assay to the Analysis of Barbiturates in Urine and Saliva K. Schwenzer A New Abuscreen OnLine II Immunoassay for the Detection of opiates 300/2000 K. Goc-Szkutnicka Abuscreen OnLine Immunoassay for the Detection of Drugs of Abuse on the Integrated Hitachi 917 Analyzer A. McNally Comparison of Derivatizing Reagents and Internal Standards for the Analysis of Opiates M. Rettinger Whizzies-A Urine Drug Screen Adulterant L. Tarnai Measurement of Nitrite in Adulterated Urine Samples by HLPC J. Singh Determination of Five Abused Drugs in Nitrite Adulterated Urine by Immunoassays and GC/MS J. Tsai Gravity-Detect and pH-Detect Assays for Urine Adulteration Testing B. Zemetra

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