| 08.00-17.30 | Registration |
| 08.30-17.30 | Poster Display 1 - Strad/Hunt/Delacombe rooms (Hilton) |
| 08.30-17.30 | Trade Displays - First Floor, Hilton hotel
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| 08.30-10.00 | OPENING CEREMONY AND PLENARY SPEAKERS
Chief Justice John Philips
Prof. Olaf Drummer
A/Prof David Ranson
President Dr. Marilyn Huestis
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| PL1 | PLENARY LECTURE
UNLOCKING THE SIGNIFICANCE OF FORENSIC TOXICOLOGY RESULTS
Dr Marilyn Huestis - 30 minutes
Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, NIH, Baltimore, MD, USA
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| PL2 | PLENARY LECTURE
USE OF LC-MS IN FORENSIC TOXICOLOGY
Prof. Aldo Polettini - 30 minutes
University of Pavia, Pavia, ITALY
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| 10.00-10.30 | TEA/COFFEE BREAK AND INFORMAL POSTER SESSION
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| 10.30-12.15 | ORAL SESSION 1
EMERGING TECHNIQUES / LC-MS
Chairpersons: Prof. A. Polettini (Italy), Dr Stuart Dickson (NZ)
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| Paper 1 | Key Note 1:
USE OF GC-MS AND LC-MS FOR SCREENING IN CLINICAL AND FORENSIC TOXICOLOGY
Prof. Hans Maurer - 20 min
Department of Experimental and Clinical Toxicology, University of Saarland, Homburg, GERMANY
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| Paper 2 | THE COMPLEMENTARY USE OF GC/MS AND LC/MS FOR THE DETECTION OF LICIT AND ILLICIT DRUGS IN ORAL FLUID
FM Wylie, H Torrance, RA Anderson, A Seymour, JS Oliver
Forensic Medicine and Science, University of Glasgow, Glasgow, UK |
| Paper 3 | COMPARISON OF LC-MS/MS PRODUCT ION SPECTRA OBTAINED BY DIFFERENT INSTRUMENTS FOR LIBRARY SEARCH
M Gergov*, W Weinmann**, J Meriluoto***, J Uusitalo****
*University of Helsinki, Helsinki, FINLAND; **Institute of Legal Medicine, Freiburg, GERMANY; ***Abo Akademi University, Turku, FINLAND; ****University of Oulu, Oulu, FINLAND |
| Paper 4 | SIMULTANEOUS DETECTION AND QUANTITATION OF 21 DRUGS OF ABUSE AND THEIR METABOLITES IN ORAL FLUID USING LIQUID CHROMATOGRAPHY - ELECTROSPRAY MASS SPECTROMETRY
H Torrance, F M Wylie, J S Oliver
Forensic Medicine and Science, University of Glasgow, Glasgow, UK |
| Paper 5 | DETERMINATION OF RARE DRUGS IN FORENSIC CASES BY LC/MS/MS
SS Johansen, JL Jensen
Department of Forensic Chemistry, Institute of Forensic Medicine, University of Copenhagen, DENMARK |
| Paper 6 | POST-MORTEM DETECTION OF DOXACURIUM AND ITS BREAKDOWN PRODUCTS BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY
MA Montgomery*, MA LeBeau*, JA Felo** , and AJ Jenkins**
*Federal Bureau of Investigation Laboratory, Quantico, VA, USA; **The Office of the Cuyahoga County Coroner, Cleveland, OH, USA |
| Paper 7 | IMPROVEMENT OF A MASS SPECTRA LIBRARIES FOR LC-MS-MS AND ITS APPLICATIONS IN FORENSIC TOXICOLOGY FOR GENERAL UNKNOWN SCREENING AND TARGET COMPOUND ANALYSIS
CA Mueller*, A Schreiber**, M Gergov***, B Maralikova*, W Weinmann*
*Institute of Legal Medicine, Forensic Toxicology, University Hospital, Freiburg, GERMANY; **Applied Biosystems, Darmstadt, GERMANY; ***University of Helsinki, Department of Forensic Medicine, Helsinki, FINLAND
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| | Questions and Answers
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| 12.15-13.30 | LUNCH BREAK AND INFORMAL POSTER SESSION
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| 12.15-13.30 | STA committee meeting of TIAFT
Hotham room (1st floor Hilton)
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| 13.30-15.00 | ORAL SESSION 2
ALTERNATIVE SPECIMENS 1 - ORAL FLUID
Chairpersons: Dr Hee-Sun Chung (South Korea), Dr Pascal Kintz (France)
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| Paper 1 | PREVALENCE OF ILLICIT AMPHETAMINE USE DETECTED IN ORAL FLUID FROM INDIVIDUALS PRECRIBED DEXAMPHETAMINE
GAA Cooper, C Hand
Cozart Bioscience Ltd, Abingdon, Oxfordshire, UK
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| Paper 2 | AN INTEGRATED DEVICE FOR ORAL FLUID COLLECTION, TRANSPORT AND ON-SITE TESTING FOR DRUGS OF ABUSE
D Baldwin, C Hand, A Jehanli
Cozart Bioscience Ltd, Abingdon, Oxfordshire, ENGLAND
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| Paper 3 | ANALYSIS OF MARIJUANA SMOKERS USING THE UPLINK RAPID DRUG TEST
R. Sam Niedbala, Salvatore Salamone, Keith Kardos, Girish Parmar, Dean Fritch
OraSure Technologies; Bethlehem, Pennsylvania, USA
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| Paper 4 | DETECTION OF OPIOIDS IN ORAL FLUID AND IDENTIFICATION OF HEROIN USE
JB Clarke*, DF Fritch**, N Koenig***, P Davis***, J Sell***
*Altrix Healthcare Plc, Warrington, Cheshire, United Kingdom; **OraSure Technologies Inc, Bethlehem, Pennsylvania, USA; ***Health Network Laboratories, Allentown, Pennsylvania, USA
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| Paper 5 | EVALUATION OF NOVEL ON-SITE TEST 'SMARTCLIP' FOR DRUG OF ABUSE TESTING USING SALIVA BY GERMAN POLICE
S Fellner*, HY Chen**, A Foo**, M Guan**, N Lange***, S Voß*, M Eckermann*, B Lindner*
*EnviteC-Wismar GmbH, Wismar, GERMANY; **Genelabs Diagnostics Pte Ltd, Singapore; ***Thueringer Polizeiverwaltungsamt, Erfurt, GERMANY
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| Paper 6 | OPIATE TIME COURSE STUDY WITH ORATECTTM - A ONE STEP ONSITE ORAL FLUID RAPID DRUG SCREEN
RC Wong, B Wong, C Tran
Branan Medical Corporation, Irvine, Ca, USA
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| Paper 7 | LOVE PARADE 2003 - DRUG CONTROLS ON GERMAN ROADS
S Steinmeyer*, M Vogel*, M von Gahlen*, M Spitzbarth*, P Konstantinidou**, RS Niedbala****, D Fritch****, J Mahn***, A Manns*
*Dräger Safety AG & Co. KGaA, Luebeck, Germany; **University of Applied Science, Albstadt-Sigmaringen, Germany; ***Drägerwerk AG, Lübeck, Germany; ****Orasure Technologies Inc, Bethlehem, PA, USA
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| | Questions and Answers
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| 15.00-15.30 | TEA/COFFEE BREAK AND INFORMAL POSTER SESSION
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| 15.30-18.00 | SPONSORED BY DRAEGER SAFETY (AUSTR)
SYMPOSIUM ON DETECTION OF DRUGS IN ORAL FLUIDS
Moderator: Dr Marilyn Huestis (USA)
Panel: Prof. Alain Verstraete (Belgium), Dr Gail Cooper (UK), Dr Sam Niedbala (USA), Dr Pascal Kintz (France), Dr Stefan Steinmeyer (Germany)
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| Paper 1 | ON-SITE ORAL FLUID DRUG TESTING FOR THE DETECTION OF DRIVING UNDER THE INFLUENCE
Alain G Verstraete
Laboratory of Clinical Biology, Ghent University Hospital and Faculty of Medicine and Health Sciences, Ghent University, Ghent, BELGIUM
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| Paper 2 | ORAL FLUID DRUG TESTING IN POLICE CUSTODY AND AT THE ROADSIDE
Gail Cooper
Cozart Bioscience Ltd, Abingdon, Oxfordshire, UK
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| Paper 3 | TESTING FOR HYPNOTICS IN ORAL FLUID. ANY INTEREST IN DFSA EVIDENCE?
P Kintz
Institut de Médecine Légale, Strasbourg, FRANCE
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| Paper 4 | REVIEW OF UPLINK TECHNOLOGY FOR DRUG SCREENING IN ORAL FLUIDS
Sam Niedbala
OraSure Technologies; Bethlehem, Pennsylvania, USA
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| Paper 5 | DRÄGER DRUGTEST®: A NEW ON-SITE DRUG DETECTION SYSTEM USING ORAL FLUID
Stefan Steinmeyer
Dräger Safety AG & Co. Luebeck, GERMANY
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| 17.00-18.00 | OPEN FORUM AND PANEL DISCUSSION
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| 18.00- | Free Evening
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| 18.00-22.00 | Chemical Technologies Workshop [free]
The Use of Solid Phase Extraction in Forensic Toxicology
Dr Michael Telepchak
Ballroom
The goal of our seminar will be to review the steps, mechanisms and rationale of SPE. The seminar will examine the effects of pH and pKa on extraction recoveries, and will also review approaches for choosing the right column. Lastly, we will identify common SPE problems and appropriate solutions.
OUTLINE:
1. History, Evolution and Chemistry
2. Steps, Techniques, Mechanisms, pH, Ion Exchange Principles
3. Drug Applications
BREAK
4. Matrices, Factors Effecting Extractions, Method Development
5. Hydrolysis and Derivatization
6. Questions
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