Toxpod logoThe Toxpod is a podcast all about forensic toxicology. Produced by Tim Scott and Peter Stockham, on behalf of The International Association of Forensic Toxicologists, the podcast aims to promote conversation among forensic toxicologists everywhere. From cutting-edge research to practical lab tips, Tim and Peter delve into the fascinating (and sometimes mystifying) world of forensic toxicology and seek perspectives from others working in a range of different contexts within the field. With hundreds of listeners from every corner of the world – subscribe to The Toxpod now, and join the conversation.

2024

  • TIAFT Curry Award recipients - Tony Moffat

    Meet the giants upon whose shoulders modern toxicologist stand upon! In the first of a series on winners of TIAFT's prestigious Alan Curry Award, Peter is joined by Tony Moffat, 2013 winner. He is still contributing to our field after more than 50 years.

    Listen here

2023

  • TIAFT Bulletin preview - Issue 53(3)

    We'll be previewing issues of the TIAFT Bulletin as they are released every few months.

    Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • October 26 - NPS Update - October 2023

    Keeping up to date with New Psychoactive Substances is hard! We've assembled a crack team of experts to help us do just that: Svante Vikingsson (TIAFT NPS Committee chair), Conor Crean (UNODC) and Alex Krotulski (CFSRE.

    These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss the dropoff in new substances compared to last year, the effect of international controls, and how best to gather and then communicate information on NPS to forensic labs.

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  • October 1 - Lana Brockbals

    Tim is joined by Lana Brockbals to discuss her research into a number of interesting areas in forensic toxicology, including post-mortem drug changes and metabolomics.

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  • September 20 - On the Spot at TIAFT2023 - Part 2

    At the TIAFT2023 conference in Rome, Peter caught up with a few fellow toxicologists to talk about their work.

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  • September 15 - On the Spot at TIAFT2023 - Part 1

    At the TIAFT2023 conference in Rome, Peter caught up with a few fellow toxicologists to talk about their work.

    Listen here
  • July 30 - TIAFT Bulletin Preview - Issue 53(2)

    We'll be previewing issues of the TIAFT Bulletin as they are released every few months.

    Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • July 17 - Forensic Workplace Trauma

    As forensic scientists, we're exposed to some pretty awful things during the course of our work. In this episode we talk with psychologist Samantha Schiro about her recent publication, "Occupational exposure to traumatic evidence and posttraumatic stress symptoms in forensic science professionals: Prevalence and patterns".

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  • June 14 - Helena Teixeira

    Tim is joined by Helena Teixeira, from the National Institute of Legal Medicine in Coimbra, Portugal.

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  • June 1 - Toxpod vs The Machine

    Artificial Intelligence is quickly becoming one of the key tools in all fields of science. In this episode we look at how it's being used in forensic toxicology, and how it might be used in the future. Special thanks to Stephen Trobbiani for participating in this episode. Here is a link to that NPS paper that Pete mentioned.

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  • May 8 - TIAFT - Then and Now (live from London)

    Did you know that TIAFT presidents have a synergistic effect? Recorded live at the TIAFT 60th Jubilee in London, this panel discussion hosted by Nikolas Lemos features a bunch of former TIAFT presidents giving their perspectives on a wide range of issues facing forensic toxicologists. Thanks to all for participating, and here's to the next 60 years!

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  • April 21 - NPS update April 2023

    Keeping up to date with New Psychoactive Substances is hard! We've assembled a crack team of experts to help us do just that:

    • Michael Evans-Brown, EMCDDA
    • Conor Crean, UNODC
    • Alex Krotulski, CFSRE

    These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss Early Warning Systems and potential changes in the synthetic cannabinoid market. In this episode we discuss an increasing trend of xylazine in fentanyl supplies, the recent scheduling of some NPS by the United Nations, and the emergence of semi-synthetic cannabinoids,/a> including HHC.

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  • April 5 - TIAFT Bulletin Preview - Issue 53(1)

    We preview the first Bulletin issue of 2023.

    Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • March 7 - 5 in 30 (Mushrooms, chemical warfare, and machine learning)

    We look at 5 recent publications in the field of toxicology.
    1. Palm, E. et al. Machine learning for absolute quantification of unidentified compounds in non-targeted LC/HRMS. (2022) Molecules, https://doi.org/10.3390/molecules27031013.
    2. Bishop-Freeman, S. et al. Melatonin supplementation in undetermined pediatric deaths. (2022) Journal of Analytical Toxicology, https://doi.org/10.1093/jat/bkac033.
    3. Flament, E. et al. Determination of orellanine in human biological matrices using liquid chromatograph with high-resolution mass spectrometry detection: A validated method applied to suspected poisoning cases. (2023) Journal of Analytical Toxicology, https://doi.org/10.1093/jat/bkac018
    4. Wang, Y. et al. Operation of the anti-doping laboratory for the Beijing 2022 Olympic and Paralympic Winter Games. (2022) Drug Testing and Analysis, DOI: 10.1002/dta.3384.
    5. Otsuka, M. et al. Analysis of degradation products of Novichok agents in human urine by hydrophilic interaction liquid chromatography-tandem mass spectrometry. (2022) Forensic Toxicology, https://doi.org/10.1007/s11419-022-00656-4.

    Listen here

2022

  • December 24 - TIAFT Bulletin preview - Issue 52(4) 

    We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.

    Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • October 9 - NPS update October 2022

    Keeping up to date with New Psychoactive Substances is hard! We've assembled a crack team of experts to help us do just that:

    • Michael Evans-Brown, EMCDDA
    • Conor Crean, UNODC
    • Alex Krotulski, CFSRE

    These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss Early Warning Systems and potential changes in the synthetic cannabinoid market.

    Listen here
  • September 27 - On the Spot at TIAFT2022

    At the TIAFT2022 conference in Versailles, Peter caught up with a few fellow toxicologists: Michael Scholz (Switzerland), Brigitte Desharnais (Canada), Svante Vikingsson (USA), and Jean-Claude Alvarez (France).

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  • September 19 - A Royal Meeting (Live at TIAFT2022)

    TIAFT meetings are back! Peter is joined on stage in Versailles by Sarah Wille (Belgium), Rebecca Hartman (USA) and Jennifer Schumann (Australia) to discuss what's hot and what's not in the field of toxicology.

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  • August 28 - 5 in 30 (Semi-liquid membranes, Kamini balls and mythical creatures)

    We look at 5 recent publications in the field of toxicology
    1. Huen-Yin Tang M, et al. Ropinirole metabolite mimics a new psychoactive substance (4-HO-MET) in LC-MS/MS. (2022) Forensic Science International, https://doi.org/10.1016/j.forsciint.2021.111151.
    2. Shang, Q. et al. Multi-extraction system with identical supported semi-liquid membrane: Enhanced stability for coextraction of acidic and basic drugs. (2022) Talanta, https://doi.org/10.1016/j.talanta.2022.123485.
    3. Khan, T. Kamini, a little recognised source of illicit opioid: A case series of 12 patients. (2022) Drug and Alcohol Review, DOI: 10.1111/dar.13475.
    4. Trigg, S. The alprazolam analogue 4’-chloro deschloroalprazolam identified in seized capsules. (2022) Drug Testing and Analysis, DOI: 10.1002/dta.3325.
    5. Brooks-Lim, E. Fatal ingestion of Taxus baccata: English yew. (2022) Journal of Forensic Sciences, DOI: 10.1111/1556-4029.14941.

    Listen here
  • June 29 - TIAFT Bulletin preview - Issue 52(2) 

    We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.

    Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • May 4 - Green Analytical Toxicology with Jose Luiz da Costa

    Tim chats with Jose Luiz da Costa, Professor of Toxicology at the University of Campinas in Brazil, about his work with NPS and advancements in 'Green Analytical Toxicology'.

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  • April 28 - Hydroxymoron & Herbal toxicity - On the Spot at FACTA2022

    At the FACTA2022 conference, Peter caught up with a few fellow toxicologists: Dimitri Gerostamoulos, Naren Gunja, and Susan Britza.

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  • April 20 - Medicinal Cannabis (live at FACTA2022)

    We continue with another episode recorded live at FACTA2022 in Brisbane, Australia.

    It's a panel discussion on medicinal cannabis featuring Associate Professor Vicki Kotsirilos, Professor Olaf Drummer, Professor Thomas Kraemer, and Dr. Samuel Banister.

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  • April 13 - Old Approaches to Fresh Problems (live at FACTA2022)

    We finally attend a real life conference again, and turn the conference theme, "Fresh approaches to old problems" , on its head! Recorded live at FACTA2022 in Brisbane, Australia.

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  • April 7 - NPS update April 2022

    Keeping up to date with New Psychoactive Substances is hard! We've assembled a crack team of experts to help us do just that:

    • Michael Evans-Brown, EMCDDA
    • Conor Crean, UNODC
    • Alex Krotulski, CFSRE

    These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss Early Warning Systems and potential changes in the synthetic cannabinoid market.

    Listen here
  • April 2 - TIAFT Bulletin preview - Issue 52(1)

    We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.

    Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • February 18 - Mythbusting at TIAFT Virtual 2022

    We were at the TIAFT Virtual Conference in February! This episode is audio from a couple of sessions we did there - busting some more myths in forensic toxicology.

    Plus we had our first ever competition! Stay tuned til the end to find out who won the prestigious Toxpod mug...

    Listen here

2021

  • December 15 - TIAFT Bulletin preview - Issue 51(4)

    We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.

    Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.

    Listen here
  • October 20 - Coming to Africa(2)

    We tell the story of the TIAFT2020 conference in Capetown, South Africa - a conference that never actually happened.

    Thanks to Alicia Evans, Bronwen Davies, Lorna Martin, Marc LeBeau, Simon Elliott, Dimitri Gerostamoulos and Michaela Kenneally for taking part in this episode.

    Listen here
  • September 27 - NPS Update(2)

    Keeping up to date with New Psychoactive Substances is hard! We've assembled a crack team of experts to help us do just that:

    • Michael Evans-Brown, EMCDDA
    • Conor Crean, UNODC
    • Alex Krotulski, CFSRE

    These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss Early Warning Systems and potential changes in the synthetic cannabinoid market.

    Some info on the new class of OXIZID SCRAs

    The UNODC Tox-Portal - get involved!

    Listen here
  • June 25 - TIAFT Bulletin preview - Issue 51(2)

    We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.

    Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here. Listen here

  • June 22 - 5 in 30 (Chemometrics, single hair analysis and GC-VUV)

    We look at 5 recent publications in the field of toxicology.

    1. Polettini A, et al. LC–QTOF-MS Presumptive Identification of Synthetic Cannabinoids without Reference Chromatographic Retention/Mass Spectral Information. II. Evaluation of a Computational Approach for Predicting and Identifying Unknown High-Resolution Product Ion Mass Spectra. (2021) Journal of Analytical Toxicology, 45(5):440-61.

    2. Kuwayama, K. et al. Development of the “selective concentration” analytical method for drug-containing hair regions based on micro-segmental analysis to identify a trace amount of drug in hair: hair analysis following single-dose ingestion of midazolam. (2021) Forensic Toxicology, 39(1):156-66.

    3. Robin, T. First-Line Toxicological Screening with Fully Automated Extraction. (2021) Journal of Analytical Toxicology, 45(3):252-68.

    4. Kranenburg, R. Spotting isomer mixtures in forensic illicit drug casework with GC–VUV using automated coelution detection and spectral deconvolution. (2021) Journal of Chromatography B, 1173:122675.

    5. Elmsjö, A. Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations. (2021) Chemical Research in Toxicology, 34(6):1496-1502.

    Listen here

  • June 15 - New Psychoactive Substances with Alex Krotulski

    We chat with Alex Krotulski about his work with CFSRE and NPS Discovery. You can find out more about these initiatives, and access the many resources they produce, at www.npsdiscovery.org. Listen here

  • June 8 - Are toxicologists too sensitive?

    Modern forensic toxicologists are able to detect tiny amounts of drugs in a sample. Is it possible we are now too sensitive? Listen here

  • June 1 - Reference Standards with Jenny Button

    We chat with Jenny Button, Deputy Director of Chiron, about the use of reference standards in forensic toxicology.

    Jenny's written a book chapter about all this - it's really good! Here's a link. Listen here

  • May 25 - Activity Based Assays with Marthe Vandeputte

    Tim chats with Marthe Vandeputte about the current and potential uses of activity based assays in forensic toxicology. Listen here

    Links to a couple of Marthe's papers on the topic are below:

    Validation of activity-based screening for synthetic cannabinoid receptor agonists in a large set of serum samples

    In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances

     

  • May 18 - 5 in 30 (Impairment apps, zebrafish and Scottish prisons)

    We look at 5 recent publications in the field of toxicology. Listen here

    1. Karoly, H. et al. Effects of high-potency cannabis on psychomotor performance in frequent cannabis users. (2020) Cannabis and Cannabinoid Research, X:X, 1-9

    2. Prado, E. et al. Metabolism of synthetic cathinones through the zebrafish water tank model: a promising tool for forensic toxicology laboratories. (2021) Forensic Toxicology, 39: 73-88

    3. Chu, M. et al. Time-dependent changes in THC concentrations in deceased persons. (2021) Journal of Analytical Toxicology, 45:1-7

    4. Van Schalkwyk, F. et al. Fatal pyrrolizidine alkaloid poisoning of infants caused by adulterated Senecio coronatus. (2021) Forensic Science International, 320:110680

    5. Norman, C. et al. Large-scale evaluation of ion mobility spectrometry for the rapid detection of synthetic cannabinoid receptor agonists in
    infused papers in prisons. (2021) Drug Testing and Analysis, 13:644–663

  • May 11 - Cognitive bias with Hillary Hamnett

    We chat with Hilary Hamnett about the complex issue of cognitive bias in forensic toxicology. You can contact Hilary at HHamnett@lincoln.ac.uk, if you would like to hear more from her about cognitive bias. Listen here

  • May 4 - Positively negative

    How confident are you that your analytical methods won't miss a target analyte? In the first episode of season 4, we discuss the potential for false negative results in forensic toxicology. Listen here


Older episodes can be found here


The Toxpod is produced by:

Tim Scott (Australia)

Tim ScottTim holds a BSc (Hons) from Flinders University and has worked in the Toxicology section at Forensic Science South Australia since 2002, where his current position is Team Leader. He is an adjunct academic at Flinders University and is a member of The International Association of Forensic Toxicologists (TIAFT), the Society of Hair Testing (SOHT), the Australian and New Zealand Forensic Science Society (ANZFSS), and is a board member of the Forensic and Clinical Toxicology Association (FACTA). He loves to talk about forensic toxicology any chance he gets – although his wife and four children do not seem particularly keen to listen, which is probably why he started a podcast. His interests include drug screening using HRMS and the interpretation of post-mortem drug concentrations.

e-mail: toxpod@tiaft.org

Peter Stockham (Australia)

Peter StockhamAfter completing his BSc (Hons) in Organic Chemistry at the University of Adelaide, Peter started his scientific career in hospital research and water quality laboratories. He joined Forensic Science South Australia in 2000 and was heavily involved in the lab's early adoption of innovative LC-MS and LC-HRMS techniques. Besides his daily reporting, casework and quality responsibilities, his recent interests include analysis of hospital emergency department samples to monitor drug trends, development of NPS suspect-screening techniques, encouraging sharing of information between toxicology labs, and trying not to take life too seriously. He is a member of FACTA and ANZFSS, and is the Australian Regional Representative for TIAFT. A scientist at heart, Peter is always aware of the rare privilege it is to have a career in a field where science and service are cornerstones, and where innovation and collaboration is the norm, if not a necessity.

e-mail: toxpod@tiaft.org

The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT or their employer.