XXXV TIAFT Annual Meeting PROCEEDINGS

Index OPENING LECTURE Meeting Continuing Challenges in the Practice of Forensic Toxicology B.K. Logan Postmortem Analysis and Drug Stability Stability of Drugs Postmortem: A Review O.H. Drummer Postmortem Interpretation of beta2-Agonist Concentrations F.J. Couper, O.H. Drummer Blood and Tissue Distribution of Methanol and Formic Acid in Victims of a Massive Intoxication Due to the Ingestion of Adulterate Wine L.A. Ferrari, R.R. Nieto, M.G. Arado, Z. Wamba Distribution of Morphine Species in postmortem Tissues J. Gerostamoulos, O.H. Drummer Supercritical Fluid Extraction as a Sample Preparation Technique for the Determination of Morphine and 6-Monoacetyl-morphine in Post-mortem Blood and Vitreous Humor K.S. Scott, J.S. Oliver Drugs of Abuse and Testing Urine Drug Testing for Social Service Agencies in Nova Scotia, Canada A.D. Fraser Prevalence of Amphetamine-like Drugs in Human Urine K.A. Cole, C. Okano, B. Creghan, B. Lukey, P. Bryant, J. Magluilo, Jr, M.L. Smith Chronic Multiple Drugs Abuse with Suicidal Endpoint: Hair and other Tissue Findings. G. Asselborn, M. Yegles, R. Wennig Do the morphine blood levels of the Swiss Heroin Substitution Program influence our Forensic Interpretations? T.A. Briellmann The Toxicology of Methadone and its Involvement in Sudden Death O.H. Drummer Driving Under the Influence Psychoactive substances, drugs and driving S.D. Ferrara Morphine Toxicity and the Intoxicated Driver A.E. Hodda First Results of the "Belgian Toxicology and Trauma Study (BTTS)" A. Verstraete, R. Wennig Prevalence of Drugs of Abuse and Medication in Conspicuous Drivers - An Epidemiological Study - M.R. Moeller, M. Hartung Driving under influence: with special attention to the drugs P. Lillsunde, L. Hantula, M. Portman, A. Penttilä, T. Korte, T. Seppälä Metabolism and Disposition of Drugs Ethnic Difference in Drug Metabolism M. Yamada, Z. Kozma, J. Ikebuchi, A. Nishimura, K. Nishi Hemp Tea Versus Hemp Milk: Subjective Effects and Elimination Studies of THC and its Main Metabolites C. Giroud, M. Augsburger, L. Rivier, P. Mangin Effects of Caffeine and Saponin on Alcohol Absorption and Metabolism M. Hirose, S. Tsukamoto, T. Kanegae, E. Isobe, T. Nagoya, K. Hojo Urinary Methanol and 5-hydroxytriptophol as biochemical markers of recent drinking after alcohol has been cleared from the body A. Helander, A.W. Jones, P. Bendtsen Hair Analysis Hair Testing and Pubic Hair Testing for Drugs of Abuse for Legal Purposes in Crete A.M. Tsatsakis Free Topics Immunoaffinity extraction of alfa- and beta- amanitin for their sensitive detection in body fluids by atmospheric pressure ionization electrospray (API-ES) LC-MS C.J. Schmitt, A.A. Weber, H.H. Maurer Toxicological detection of ACE inhibitors and their metabolites in urine by GC-MS after extractive alkylation J.W. Arlt, H.H. Maurer Analytical Findings in a Suspected Case of Tampering with a morphine Pump A. Bugge, H. Mørland, L. Slørdal Fatal Exposure to Polyurethane Grout J. Tytgat, N. Bruneel, E. Stevens, P. Daenens TICTAC – a CD-ROM for the identification of tablets and capsules. J. D. Ramsey, J. M. Woolley Identification and profiles of impurities in illicit methamphetamine in Korea Y.C. Yoo, H.S. Chung, H.K. Choi, E.M. Kim, S.C. Kim, S.W. Kim Analytical Procedures The use of high selectivity MS techniques to increase the retrospectibility of the detection of the abuse of selected doping agents L. Rivier The Use of GC/MS/MS for the Detection of An Uncommon Benzodiazepine in a Urine Specimen D.T.W. Chan, V.K.K. Mok Determination of Morphine, M-6-G, M-3-G, Codeine, C-6-G and 6-MAM in Body Fluids by Means of LC-APCI-MS. M.J. Bogusz, R.D. Maier, M. Erkens, S. Driessen A Sensitive Analysis of the active metabolite of Burgodin® (Despropionyl-bezitramide) in Forensic Samples by High Performance Liquid Chromatography with Fluorescence Detection S. De Baere, E. Meyer, W. Lambert, A. De Leenheer Column packed immobilized beta-glucuronidase and arylsulfatase for the cleavage of conjugates - Stability, reusability and application in toxicological routine analysis S.W.H. Toennes, H.H. Maurer The antilipemic benfluorex leads to positive amphetamine fluorescence polarization immunoassay (FPIA) results - Studies on the metabolism and toxicological detection in urine by GC-MS and FPIA T. Kraemer, F.D. Sick, H. H. Maurer POSTERS Physiological and Histopathological Changes on the effects of BPMC (OSBAC) Carbamate Insecticide on Chickens H.A. Mekkawy, A.A. Massoud, E.M. Hammouda, M. Hassan Mutagenic and Teratogenic Effects of Cyanophos (CYANOX) Organophosphorus Insecticide on Chickens H.A. Mekkawy, A.A. Massoud, E.M. Hammouda, M.A. Hassan The Distribution at User Levels of Narcotics in Denmark K.W. Simonsen, E. Kaa, E. Nielsen Dynamic Modification in TLC of Basic Drugs on Silica Gel R. Giebelmann Qualitative analysis by Mass-Spectrometry of "Ecstasy" tablets: a specific study of quantitative distribution of MDMA and MDEA relative to tablets morphology M. Giusiani, A. Cappellini Quantitative Screening for Silyl Derivatized Benzodiazepines in Blood by Dual-Column Gas Chromatography with Computerized Identification I. Rasanen, I. Ojanperä, E. Vuori Autoantibodies and Immunoglobulins in Workers Exposed to Mercury Vapours J. Kolenic, A. Ciderová, D. Palcáková, J. Petrovicová, P. Kolenic, T. Kralová The consequences of caffeine administration to mice with toxic liver lesions induced by paracetamol. V. Gligor, R. Gligor, E. Lazar, E. Potencz Analysis of Fenthion in Postmortem Samples by HPLC with Diode-Array Detection and GC/MS Using Solid-Phase Extraction E. Meyer, D. Borrey, W. Lambert, C. Van Peteghem, M. Piette, A. De Leenheer Application of Supercritical Fluid Extraction with Freeze-drying to Analysis of Benzodiazepine Metabolites in Blood Samples K. Takaichi, Y. Kumooka, H. Ohki Evaluation of the Diagnostic Performance of the Boehringer Mannheim CEDIA® LSD Assay. A.G. Verstraete, S. Steyaert Solid-Phase Extraction and Determination of ß-Agonists in Urine by HPLC with Electrochemical Detection J. Bosman, K. Ensing, J.P. Franke, A. Koole, R.A. De Zeeuw GC/MS confirmation of Buprenorphine and Norbuprenorphine in urine D.H. Strand, T. Berg, I. Leirseth, A.S. Christophersen Validation of an Ion-Trap GC/MS Method for Determination of Cocaine and Metabolites and Cocaethylene in Post Mortem Whole Blood A.A.M. Chasin, A.F. Mídio Immunohistochemical Investigation of Pulmonary Surfactant in Fatal Poisoning B. Zhu, L. Quan , K. Ishida , S. Oritani, M. Imura, M.Q. Fujita , H. Maeda , M. Ogawa , T. Tanaka, N. Tanaka, S. Komura, T. Tsuji Simultaneous Determination of Cyanide in Automated Screening of Volatile Substances in Biological Fluids by Head-Space Gas Chromatography/Mass Spectrometry S. Oritani, M.Q. Fujita, K. Ishida, B. Zhu, H. Maeda Methadone Saliva:Blood Ratios in Methadone Maintenance Patients C. Malcolm, J. S. Oliver Comparison Between Solid-Phase Extraction and Supercritical Fluid Extraction and for the Analysis of Morphine from Whole Blood D.L. Allen, K.S. Scott, J.S. Oliver Comparison of Drug and Alcohol Levels Measured in Victims of Fatal Road Traffic Accidents in the Strathclyde Region of Scotland Over the 2 Year Period 1995-96 A. Seymour, J. S. Oliver Improved Extraction of Methadone and its Metabolites from Whole Blood Using Isolute Confirm Mixed-Mode SPE Columns. G.A.A. Cooper, J. S. Oliver Methylpentynol Intoxication - a Case Report C. Brehmer, D. Frangi, P.X. Iten Determination of Arsenic in Horse Urine using Microwave Digestion and Inductively Coupled Plasma Atomic Emission Spectrometry V. Coopman, J. Cordonnier, T. Van Moortel Pesticides deposition in hair: Preliminary results of a model study of methomyl incorporation into hair of rabbits A.M. Tsatsakis, M.I. Tutudaki, M.N. Tzatzarakis, K. Psaroudakis, G.P. Dolapsakis, M.N. Michalodimitrakis Determination of Phenytoin in Human Head Hair T. Psillakis, A. Tsatsakis, A. Stefis, E. Kalpaxidu, G. Daskalakis, S. Petrutsu, E. Pallis, G. Kliafas Cases of Acute Poisoning in the Region of Crete M. Christakis-Hampsas, A.M. Tsatsakis, P. Assithianakis, A. Alegakis, M. Tutudakis, E.N. Michalodimitrakis Acute Fenthion and Omethoate Poisoning A. Manousakis, A.M. Tsatsakis, M. Anastasakis, M. Tzatzarakis, P. Agouridakis, K. Katsanoulas Characterisation of Cannabis Plants Phenotypes Based on the Analysis of Active Substances M. Dimopoulou, M. Tutudaki, A. Tsatsakis, E. Michalodimitrakis Methamphetamine blood concentrations in 17 fatal cases Y.C. Yoo, H.S. Chung, H.K. Choi, W.T. Jin, M.J. Park, W.K. Yang A Simple and Rapid Analysis of Irritants in Tear Gas Sprays by Capillary Column Gas Chromatography-Mass Spectrometry N. Tsunoda, Y. Seto, M. Kataoka, H. Ohta A Highly Sensitive HPLC Detection of Methamphetamine and Amphetamine in Hair Using Chemiluminescence Detection N. Takayama, S. Tanaka, K. Hayakawa Perspiration versus saliva in road side testing. Physiological and biochemical properties on drug secretion and implications G. Skopp, L. Pötsch The Possibility of Inhibition of Topoisomerase I activity by Methamphetamine T. Sawaguchi, A. Sawaguchi Cyanobacterial Hepatotoxins: Structure and Analysis A. Pelander, I. Ojanperä, E. Vuori ONTRAK TESTCUP®-5: A Multi-analyte Immunoassay Device for On-Site Drug Testing S-C.J. Tsai, J. Towt, C. Kravec, B. Oades, F. Rashid, L. Talbot, B. Twarowska, S.J. Salamone Carbohydrate-Deficient Transferrin and Chronic Alcohol Abuse A. D'Ottavi, F. Caracciolo Experience in Congener Analysis with GC/MS W. Römhild, H. Wittig, D. Krause, H. Bartels The Automated Preparation and Analysis of Barbiturates in Human Urine and Serum using A PrepStation and GC/MS System A. Namera*, M. Yashiki, K. Okada, Y. Iwasaki, T. Kojima Drug Abuse Among Truck Drivers in Three Different Regions of Brazil O.A. Silva, J.M.D. Greve, M. Yonamine Toxicological Findings in a Fatal Case of Multidrug Poisoning. A Typical Example of a Polish Drug Addict M. Kala, W. Lechowicz, R. Stanaszek Laudanosine in Biological and Non-biological Material: A Two Case Report M. Kala, W. Lechowicz, K. Madej, R. Stanaszek Thallium Poisoning J.K. Sadlik Polish "Kompot" and Other Opiate Containing Products. A Comparative Study M. Kala, W. Lechowicz Ephedrone - new street drug synthetized from Proasthmin E. Janowska, E. Chudzikiewicz, W. Lechowicz Investigations of patients during constant dose methadone treatment considering individual hair growth L. Pötsch, H.P. Eser, G. Skopp, M.R. Moeller Identity testing of alternative samples used in forensic toxicology L. Pötsch, P.M. Schneider, J. Lummer, G. Skopp Drugs of abuse Screening by TRIAGETM Indirectly in Postmortem specimens H. Tsoukali, N. Raikos Modifying the Absorption Rate of Ethanol by Intake of a Drop Containing Menthol E. Jeszenszky, I. Kovacs, T. Varga A Specific Method for the Determination of Sodium Fluoroacetate in Biological Samples Using Ion-Exchange Chromatography, HPLC and Spectrophotometry A.F. Midio, R.L.M. Moreau, N.M. Nakaharada Vitreous Humor as an Alternative and Complementary Biological Fluid in the Determination of Ethanol Levels in Decomposed and Nondecomposed Bodies I.V. Lima, A.F. Midio Redistribution studies of Morphine and Metabolites J. Gerostamoulos, O.H. Drummer Comparison Between Ethanol Levels of Vitreous Humour of Both Eyes in the Same Individual A.P. Sousa, D.N. Vieira, M.M.F. Oliveira, E.P. Marques, P.V. Monsanto Influence of Preservation Time in Blood Ethanol Levels B.S. Silva, D.N. Vieira, M.F. Oliveira, E.G. Pinho Marques, P.V. Monsanto Fatal Acute Poisoning with Lindane Insecticide – A Case Report E.G. Pinho Marques, M.M.F. Oliveira, P.V. Monsanto, P. Proenca, F. Castanheira, A.M. Castanheira, M.T. Ávila GCD Quantitation of Opiates as Propionyl Derivatives in Blood S. Mykkänen, J. Seppälä, K. Ariniemi, T. Korte, T. Seppälä, P. Lillsunde Amphetamine- and Phenylpropanolamine Derivative Related Deaths in The Netherlands from 1994 to 1997: Toxicology and Pathology K.J. Lusthof, B. Ruiter, B.E. Smink, P.G.M. Zweipfenning, G. van Ingen, R. Visser The determination of Amphetamine, Methamphetamine, MDMA, MDEA and MDA in whole blood by solid phase extraction and gas chromatography/mass spectrometry L.J.C. Peschier, J. Nunes Roque, K.J. Lusthof, P.G.M. Zweipfenning Sensitive Determination of Tetrodotoxin in Serum by GC/MS Y. Ohtsuka, H. Tokunaga, S. Fukushima, K. Kudo, T. Imamura, N. Jitsufuchi, N. lkeda Plasma Concentrations of Antipsychotic Drugs in Psychiatric Inpatients H. Tokunaga, K. Kudo, T. Imamura, N. Jitsufuchi, Y. Ohtsuka, N. Ikeda Diethylenglycol (DEG) in Human Organs from Victims of a Massive Intoxication with Contaminated Propolis Syrup L.A. Ferrari, M.G. Arado, Z. Wamba, M. Stoichevich, S. Stoichevich Incidence of Drugs of Abuse and Alcohol in Suicides Occurred in the Province of Buenos Aires in 1994, 1995 and 1996 Z. Wamba, L.A. Ferrari; R.R. Nieto; M.G. Arado, C.H. Colangelo, C. Nardo, N. Sredcoff, S. Stoichevich Immunometric Screening of Main Drugs of Abuse on Air A. Menegozzo, G. Fazzin, M. Spampatti Determination of LSD in Urine by Solid Phase Extraction and GC/MS Detection S. Corcione, J. Ortuño, M.L. González, A.G. Verstraete, R. Ventura, R. de la Torre, J. Segura An Autopsy Case of Glyphosate Herbicide, Touchdown® Poisoning and Detection of Glyphosate using HPLC Y. Sato, S. Matsumura, K. Hayashi, T. Takagi, A. Ueno, T. Shoji, M. Kajiwara, T. Sudo, T. Watanabe, H. Kashiwade, T. Mukai, T. Endo GC/MS Analysis of Urinary Hippuric Acid Using Simple Sample Preparation K. Hara, S. Kashimura, M. Morinaga, M. Kageura Evaluating Some Extraction Procedures for Opiates from Human Hair S. Pichini, I. Altieri, M. Pellegrini, R. Pacifici, P. Zuccaro, V. Ottaviano, C. Furnari Postmortem Tissue Distribution of Opiates in Various Maternal and Fetal Specimens After Fatal Heroin Intoxication S. Iwersen, A. Schmoldt A Case of Lidocaine Poisoning A. Sawaguchi, T. Sawaguchi, O. Ohue The Evaluation and Introduction into Forensic Casework of a Commercially Avaliable Non-Isotopic Immunoassay for Drugs of Abuse J. Evans Anabolic Steroid 4-Androsten-3,17-Dione: Abuse and Detection in Urine Uralets V.P., Gillette P.A., Latven R.K. Biliary Analysis of Dextropropoxyphene and Norpropoxyphene by Solid Phase Extraction N.P. Lemos, R.A. Anderson External Quality Assessment of the GTFCh M. Herbold, G. Skopp, R. Aderjan